Focus on diabete tipo 2
Dalle 83rd Scientific Sessions dell’American Diabetes Association
REPORT & SLIDE KIT
Diabete tipo 2 - Calo ponderale
profilo di sicurezza simile agli agonisti recettoriali del GLP-1 iniettivi
Efficacia dell’agonista recettoriale non peptidico del GLP-1 orale orforglipron in persone obese o sovrappeso: uno studio di fase 2
Diabete tipo 2 - Compenso glicemico
ONWARDS 3: compenso glicemico migliore con insulina icodec settimanale vs insulina degludec giornaliera nel DT2 insulino-naïve
Diabete tipo 2 - DT2 e tumori
Associazione fra età all’insorgenza del diabete e rischio oncologico successivo
Interviste agli esperti italiani
“SURPASS(ing)” an Era of Basal-Bolus Insulin Therapy - Tirzepatide vs. Insulin Lispro TID Added-on to Poorly Controlled Basal Insulin-Treated in Type 2 Diabetes
13
Tirzepatide vs. insulina lispro TID: qual è il disegno dello studio?
96
A 52 settimane, quali i risultati, soprattutto in termini di calo ponderale?
242
Quali sono stati gli eventi avversi più comuni con tirzepatide?
Tirzepatide Reduces Albuminuria in Patients with T2D - Post Hoc Pooled Analysis of SURPASS 1-5
13
Quali i risultati della post hoc pooled analysis dei SURPASS 1-5?
176
La riduzione dell’UACR è stata maggiormente significativa in quali gruppi?
262
Nelle persone con DT2, comprese quelle con funzionalità renale ridotta, tirzepatide supporta un potenziale effetto protettivo del rene?
Interviste agli esperti internazionali
SURMOUNT 2 Trial Results and Potential Role of Tirzepatide in Treating Obesity in Type 2 Diabetes
13
What’s so significant about the SURMOUNT 2 trial?
168
Weight loss in SURMOUNT 2 was somewhat less than what was seen in SURMOUNT 1, how do you explain that?
301
What additional studies are in the pipeline with tirzepatide?
Retatrutide (LY3437943), a Novel GIP/GLP-1/Glucagon Receptor Triagonist—Obesity, NAFLD, and T2D Phase 2 Trial Results
13
What is the design and top line results of this phase 2 study with retatrutide?
152
Were there any predictors of weight loss?
Banting Medal: Overcoming Obesity—The Discovery of Multi Receptor Drugs
13
Dual incretin agonists are now well known in the therapeutic armamentarium for type 2 diabetes. What about triagonists?
49
What does the future hold for antiobesity agents?
89
Can multitarget agonists help personalize treatment of type 2 diabetes?
Initial Combination Therapy in Type 2 Diabetes Mellitus
13
How does a stepwise approach compare to initial combination therapy?
703
What are the best drugs to use in combination?
755
Are DPP-4 inhibitors out of the picture?
WEBCAST
ADA 2023 – Focus on weight and T2D
Harnessing biology: an update on new treatment options and data in T2D